Skin · Cosmetic octapeptide · Research guide
Snap-8
Snap-8 (Acetyl Octapeptide-3) is an octapeptide extension of Argireline (Acetyl Hexapeptide-3). Both are studied in cosmetic-research literature for effects on facial muscle contraction signaling relevant to expression lines.
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Mechanism
- SNARE complex modulation. Interferes with the SNARE-complex-mediated release of acetylcholine at the neuromuscular junction, reducing muscle contraction — same target class as botulinum toxin, but via a different mechanism.
Common research protocols
Dosing information below reflects published research literature. It is not medical advice and is not a treatment plan.
- Route. Subcutaneous injection.
Evidence at a glance
- Human data. Small cosmetic-industry studies. Not FDA-approved for therapeutic use.
Reconstitution & handling
Lyophilized peptides ship as freeze-dried powder. Reconstitute with bacteriostatic water; refrigerate the reconstituted vial. Use the reconstitution calculator to get syringe-unit readings for your target dose. General reconstitution and syringe guidance in the How We Work page.
Primary-literature list for this guide available on request via contact.
Further reading — external professional sources
- Argireline (parent hexapeptide) — Wikipedia
- PubMed — search "acetyl octapeptide-3 OR SNAP-8"
- ClinicalTrials.gov — trials for "acetyl octapeptide"
Links open in a new tab. Private Supply is not affiliated with these sources.