Semax

Semax is a synthetic heptapeptide developed in Russia and based on a fragment of adrenocorticotropic hormone (ACTH 4-10). It has been studied in Russian clinical literature for cognitive endurance, stroke recovery, and effects on BDNF (brain-derived neurotrophic factor) expression.

Mechanism

• BDNF modulation. Studies report upregulation of BDNF expression.
• Neuroprotection. Investigated in ischemic stroke recovery models.

Common research protocols

Dosing information below reflects published research literature. It is not medical advice and is not a treatment plan.

• Common route. Intranasal spray. Not typically injected.

Evidence at a glance

• Regulatory status. Approved in Russia for stroke recovery; not FDA-approved.

Reconstitution & handling

Lyophilized peptides ship as freeze-dried powder. Reconstitute with bacteriostatic water; refrigerate the reconstituted vial. Use the reconstitution calculator to get syringe-unit readings for your target dose. General reconstitution and syringe guidance in the How It Works page.

Primary-literature list for this guide available on request via contact.