Epitalon

Epitalon (also spelled Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by the Khavinson group in Russia. It has been studied primarily in Russian literature for effects on telomerase activity, circadian regulation, and cellular aging biomarkers.

Mechanism

• Telomerase activity. In vitro studies report upregulation of telomerase activity in somatic cells.
• Pineal / circadian effects. Studied for effects on melatonin and cortisol rhythms.

Common research protocols

Dosing information below reflects published research literature. It is not medical advice and is not a treatment plan.

• Common research use. Short courses (typically 10-20 day cycles), subcutaneous or intranasal.

Evidence at a glance

• Human data. Small Russian clinical studies; limited replication in Western literature.
• Status. Not FDA-approved.

Reconstitution & handling

Lyophilized peptides ship as freeze-dried powder. Reconstitute with bacteriostatic water; refrigerate the reconstituted vial. Use the reconstitution calculator to get syringe-unit readings for your target dose. General reconstitution and syringe guidance in the How It Works page.

Primary-literature list for this guide available on request via contact.